I got 2006 dodge caravan when i drive it on highway as soon as reach 80kms the van start shaking after 80kms back nice drive

I think this vehicle has a broken mount for the engine or transmission!

My van cuts off after driving on a long stretch of highway. Around town it does pretty good. It starts back up after ten or fifteen mins. I changed the oil, oil filter, coil pack new spark plugs, and fuel fliter. It still does it. Does any one know what this could be???? O its a 2001 dodge caravan

If no "check engine" light on, perhaps a new fuel filter would be a good place to start, and have fuel pressure tested if it doesn't help. More info, such as does it only on highway driving, or all the time, when was last tune-up, fuel system cleaned etc?

It very well could be a problem lurking there. My advice is to have the transmission fluid/filter changed asap.

100 miles an hour that's pretty fast a couple of things unbalanced wheels front end bushings ,tie rods rockin pinion and alignment

Your engine is design to prevent it from red lining by accidently stepping on the gas while it is parked.

Sounds like ignition switch. Everything works when key is twisted full forward but when released contact is lost.

SOUND LIKE SEVERE ENGINE MISFIRE HAVE VAN SCANNED AUTO ZONE WILL DO IT FOR FREE .BUT MAKE SURE FUEL FILTER NOT STOPPED UP MAKE SURE PLUGS AND WIRES IN GOOD SHAPE.FILL FUEL TANK UP.PUT A BOTTLE FUEL INJECTOR CLEAN IN FUEL TANK.TO CLEAN OUT FUEL INJECTORS WHILE YOU DRIVING THE VECHICLE.ALSO BAD COIL OR COILS WILL CAUSE ENGINE TO MISFIRE SHAKE.

Your Caravan has no rear differential. The van is a front wheel drive, you may have a bad brake or your spare tire under the back of the van is lose. the other thing to look for in the back is the rear shocks could be broken or lose. Good luck and keep me posted, be glad to help get your van running 100% again soon. 

I've had several of these vans with this problem, check the transaxle for low fluid. Each of mine would start shaking when the fluid was low.